Probability of identity by descent in metapopulations.

Second cousins with cystic fibrosis and no common ancestor who is a carrier.

Second cousins with cystic fibrosis and no common ancestor who is a carrier Park et al,' in this Journal, reported on second cousins with cystic fibrosis (CF) who did not share a CFTR allele identical by descent. They concluded that this situation was 312 times less likely than sharing a CFTR allele inherited from a common ancestor. Previously we reported on a CF patient from a consanguineous m...

A Revised Li-Sacks Formula For Calculating the Probability of Identity-by-Descent Proportion

Detecting environmental impacts on metapopulations of mound spring invertebrates: assessing an incidence function model.

We use a stochastic patch occupancy model of invertebrates in the Mound Springs ecosystem of South Australia to assess the ability of incidence function models to detect environmental impacts on metapopulations. We assume that the probability of colonisation decreases with increasing isolation and the probability of extinction is constant across spring vents. We run the models to quasi-equilibr...

Recombination, gene conversion, and identity-by-descent at three loci.

We investigate the probabilities of identity-by-descent at three loci in order to find a signature which differentiates between the two types of crossing over events: recombination and gene conversion. We use a Markov chain to model coalescence, recombination, gene conversion and mutation in a sample of size two. Using numerical analysis, we calculate the total probability of identity-by-descen...

Effect of Cognitive-Behavioral Group Therapy on Identity Crisis and Pregnancy of Pregnant Women Applying for IVF

Abstract Objective: The problem of infertility as a stressful event is associated with many psychological problems. The purpose of this study was to determine the effect of cognitive-behavioral group therapy on identity crisis and pregnancy probability of infertile women seeking IVF. Method: A quasi-experimental research with pre-test, post-test with control group was the statistical populati...